A. Stabell, J. Hawkins, M. Li, X. Gao, M. David, W. Press and S. Sawyer |
||
Non-Human Primate Schlafen11 Inhibits Production of Both Host and Viral Proteins | ![]() |
|
PLOS Pathogens 12 (12);e1006066. doi:10.1371 |
D. Otero, N. Fares-Frederickson, M. Xiao, D. Baker and M. David |
||
IFN-β Selectively Inhibits IL-2 Production through CREM-Mediated Chromatin Remodeling | ![]() |
|
Journal of Immunology (2015), doi:10.4049 |
T. Ohkuri, A. Ghosh, A. Kosaka, J. Zhu, M. Ikeura, M. David, S. Watkins, S. Sarkar and H. Okada | ||
STING contributes to antiglioma immunity via triggering type I IFN signals in the tumor microenvironment | ![]() |
|
Cancer Immunol Res. 2014 Dec;2(12):1199-208. doi: 10.1158 |
K. Mowen and M. David | ||
Unconventional post-translational modifications in immunological signaling | ![]() |
|
Nat Immunol. 2014 Jun;15(6):512-20. doi: 10.1038 |
M. Abdel-Mohsen, R. Raposo, X. Deng, M. Li, T. Liegler, E. Sinclair, M. Salama, H. Ghanem, R. Hoh, J. Wong, M. David, D. Nixon, S. Deeks and S. Pillai |
||
Expression profile of host restriction factors in HIV-1 elite controllers | ![]() |
|
Retrovirology, Vol.10, 106- (2013), doi:10.1186/1742-4690-10-106 |
D. Otero, D. Baker and M. David | ||
IRF7-Dependent IFN-β Production in Response to RANKL Promotes Medullary Thymic Epithelial Cell Development | ![]() |
|
Journal of Immunology (2013), doi:10.4049 |
M. Li, E. Kao, X. Gao, H. Sandig, K. Limmer, M. Pavon-Eternod, T. Jones, S. Landry, T. Pan, M. Weitzman and M. David | ||
Codon-usage-based inhibition of HIV protein synthesis by human schlafen 11 | ![]() |
|
Nature (2012), doi:10.1038 |
J. Gonzalez-Navajaz, J. Lee, M. David and E. Raz | ||
Immunemodulatory Functions of type I Interferons | ![]() |
|
Nature Reviews|Immunology, Vol. 12 (2012), 125-135 |
E. Chiang, V. Veckman, K.Limmer and M. David | ||
Phospholipase Cg-2 and Intracellular Calcium Are Required for LPS-induced TLR4 Endocytosis and IRF3 Activation | ![]() |
|
Journal of Biological Chemistry, Vol. 287, No. 6 (2012), 3704-3709 |
H. Moro, D. Otero, Y. Tanabe and M. David | ||
T Cell-Intrinsic and -Extrinsic Contributions of the IFNAR/STAT1-Axis to Thymocyte Survival | ![]() |
|
PLoS ONE (2011), doi:10.1371 |
M. David | ||
Interferons and MicroRNAs | ![]() |
|
Journal of Interferon & Cytokine Research, Vol. 30, (2010), 825-828 |
I. Pedersen, D. Otero, E. Kao, A Miletic, C. Hother, E. Ralfkiaer, R. Rickert, K. Groenbaek and M. David | ||
Onco-miR-155 Targets SHIP1 to Promote TNFa-dependent Growth of B cell Lymphomas | ![]() |
|
EMBO Molecular Medicine, Vol. 1, (2009), 288-295 |
I. Pedersen and M. David | ||
microRNAs in the immune response | ![]() |
|
Cytokine, Vol.43, (2008), 391-394 |
I. Pedersen, G. Cheng, S. Wieland, S. Volinia, C. Croce, F. Chisari and M. David | ||
Interferon Modulation of cellular microRNAs as an antiviral mechanism | ![]() |
|
Nature, Vol.449, (2007), 919-922 |
R. Hoyt, W. Zhu, F. Cerignoli, A. Alonso, T. Mustelin and M. David | ||
Selective Tyrosine Dephosphorylation of Interferon-Activated Nuclear STAT5 by the VHR Phosphatase | ![]() |
|
Journal of Immunology (Cutting Edge),Vol. 179, (2007), 3402-3406 |
D. Otero, V. Poli, M. David and R.C. Rickert | ||
Inherent and Acquired Resistance to Radiation-Induced Apoptosis in B Cells: A Pivotal Role for STAT3 | ![]() |
|
Journal of Immunology (Cutting Edge),Vol. 177, (2006), 6593-6597 |
E. Chiang, O. Dang, K. Anderson, A. Matsuzawa, H. Ichijo and M. David | ||
ASK1 is Required for ROS-Mediated Activation of IRF3 by LPS | ![]() |
|
Journal of Immunology (Cutting Edge),Vol. 176, (2006), 5720-5724 |
S. Ogawa, J. Lozach, C. Benner, G. Pascual, R. Tangirala, S. Westin, A. Hoffman, S. Subramaniam, M. David, M. Rosenfeld and C. Glass | ||
Molecular Determinants of Crosstalk between Nuclear Receptors and Toll-like Receptors | ![]() |
|
Cell, Vol. 122, September 9 (2005), 707-721 |
S. Li, M. Wilkinson, X. Xia, M. David, L. Xu, A. Purkel-Sutton and A. Bhardwaj | ||
Induction of IFN-regulated factors and antitumoral surveillance by transfected placebo plasmid DNA | ![]() |
|
Molecular Therapy ,Vol. 11, No. 1 (2005), 112-119 |
Y. Tanabe, T. Nishibori, L. Su, R.M. Arduini, D.P. Baker and M. David | ||
Role of STAT1, STAT3 and STAT5 in IFNa/b Responses in T-Lymphocytes | ![]() |
|
Journal of Immunology (Cutting Edge),Vol. 174, (2005), 609-613 |
K.A. Mowen, B.T. Schurter, J.W. Fathman, M. David and L.H. Glimcher | ||
Arginine Methylation of NIP45 Modulates Cytokine Gene Expression in Effector T Lymphocytes | ![]() |
|
Molecular Cell , Vol. 15, No. 4 (2004), 559-571 |
H.Y. Cheng, P.Li, M. David, T.E. Smithgall, L. Feng and M.W. Lieberman | ||
Arsenic Inhibition of the JAK-STAT pathway | ![]() |
|
Oncogene, Vol. 23, No. 20 (2004), 3603-3612 |
W.A. Smith, B.T. Schurter, F. Wong-Staal and M. David | ||
Arginine Methylation of RNA Helicase A Determines Its Subcellular Localization | ![]() |
|
Journal of Biological Chemistry, Vol. 279, No. 22 (2004), 22795-22798 |
O. Dang, L. Navarro and M. David | ||
Inhibition of LPS-induced IFN-Regulatory Factor 3 Activation and Protection from Septic Shock by Hydroxystilbenes | ![]() |
|
Shock,Vol. 21, No. 5 (2004), 470-475 |
O. Dang, L. Navarro, K. Anderson and M. David | ||
Anthrax Lethal Toxin Inhibits Activation of IFN-Regulatory Factor 3 by Lipopolysaccharide | ![]() |
|
Journal of Immunology (Cutting Edge),Vol. 172, (2004), 747-751 |
T. Nishibori, Y. Tanabe, L. Su and M. David | ||
Impaired development of CD4+CD25+ regulatory T cells in the absence of STAT1: increased susceptibility to autoimmune disease | ![]() |
|
Journal of Experimental Medicine, Vol. 199, No. 1 (2004), 25-34 |
V. Ruvolo , L. Navarro, C.E. Sample, M. David, S. Sung and S. Swaminathan | ||
The Epstein-Barr Virus SM Protein Induces STAT1 and Interferon-stimulated Gene Expression | ![]() |
|
Journal of Virology, Vol. 77, No. 6 (2003), 3690-3701 |
W. Zhu, T. Mustelin and M. David | ||
Arginine Methylation of STAT1 Regulates Its Dephosphorylation by T cell Protein Tyrosine Phosphatase | ![]() |
|
Journal of Biological Chemistry, Vol. 277, No. 39 (2002), 35787-35790 |
J. ten Hoeve, M. Ibarra-Sanchez, Y. Fu, W. Zhu, M. Tremblay, M. David and K. Shuai | ||
Identification of a Nuclear Stat1 Protein Tyrosine Phosphatase | ![]() |
|
Molecular and Cellular Biology, Vol. 22, No. 16 (2002), 5662-5668 |
M. David | ||
Signal Transduction by Type I Interferons | ![]() |
|
BioTechniques, Vol 33, No. 4 (2002), S58-S65 |
K.Mowen and M. David | ||
Analysis of Protein Arginine Methylation | ![]() |
|
Science STKE (2001) |
W.A. Blesofsky, K. Mowen, R.M. Arduini, D.P. Baker, M.A. Murphy, D.L. Bowtell and M. David | ||
Regulation of STAT Protein Synthesis by c-Cbl | ![]() |
|
Oncogene, Vol. 20, No. 50 (2001), 7326-33 |
K. Mowen, J. Tang, W. Zhu, B.T. Schurter, K. Shuai, H.R. Herschman and M. David | ||
Arginine Methylation of STAT1 Modulates IFNa/b Induced Transcription | ![]() |
|
Cell, Vol. 104, March 9 (2001), 731-741 |
T.Deb, L. Su, L. Wong, E. Bonvini, A. Wells, M. David and G. Johnson | ||
EGF Receptor Kinase-independent Signaling by EGF | ![]() |
|
Journal of Biological Chemistry, Vol. 276, No. 18 (2001), 15554-15560 |
K.Mowen and M. David | ||
Regulation of STAT1 Nuclear Export by Jak1 | ![]() |
|
Molecular and Cellular Biology, Vol. 20, No. 19 (2000), 7273-7281 |
L. Su and M. David | ||
Distinct mechanisms of STAT phosphorylation via the IFNa/b Receptor: Selective Inhibition of STAT3 and STAT5 by Piceatannol | ![]() |
|
Journal of Biological Chemistry, Vol. 275, No. 17 (2000), 12661-12666 |
L. Navarro and M. David | ||
p38-dependent Activation of Interferon Regulatory Factor 3 by Lipopolysaccharide | ![]() |
|
Journal of Biological Chemistry, Vol. 274, No. 50 (1999), 35535-35538 |
L. Su, R. Rickert and M. David | ||
Rapid STAT phosphorylation via the B cell receptor: Modulatory Role of CD19 | ![]() |
|
Journal of Biological Chemistry,Vol. 274, No. 45 (1999), 31770-31774 |
L. Su and M. David | ||
Inhibition of B cell Receptor Mediated Apoptosis by IFN | ![]() |
|
Journal of Immunology, Vol.162, No.11 (1999), 6317-21 |
K. Mowen and M. David | ||
Role of STAT1-SH2 Domain and STAT2 in the Nuclear Translocation of STAT1 | ![]() |
|
Journal of Biological Chemistry,Vol.273, No.46 (1998), 30073-76 |
L. Navarro, K. Mowen, S. Rodems, B. Weaver, N. Reich, D. Spector and M. David | ||
Cytomegalovirus Activates Interferon Immediate Early Response Gene Expression and an IRF3 Containing ISRE-binding Complex | ![]() |
|
Molecular and Cellular Biology, Vol. 18, No. 7 (1998), 3796-3802 |
M. Sakatsume, L. Stancato, M. David, O. Silvennoinen, J. Pierce, A. Larner and D. Finbloom | ||
IFNg Activation of Raf-1 Is Jak1-dependent and p21-ras independent | ![]() |
|
Journal of Biological Chemistry, Vol.273, No.5 (1998), 3021-26 |
L. Stancato, M. Sakatsume, M. David, P. Dent, F. Dong, E. Petricoin, J. Krolewski, O. Silvennoinen, P. Saharinen, J. Pierce et al. | ||
Beta Interferon and Oncostatin M Activate Raf-1 and Mitogen Activated Protein Kinase through a JAK1 dependent Pathway | ![]() |
|
Molecular and Cellular Biology, Vol. 17, No.7 (1997), 3833-40 |
M. David, Gaochao Zhou, R. Pine, J. Dixon and A. Larner | ||
The SH2-Domain Containing Tyrosine Phosphatase PTP1D is Required for IFNa/b - induced Gene Expression | ![]() |
|
Journal of Biological Chemistry, Vol. 271, No. 27 (1996), 15862-65 |
M. David, E. Petricoin and A. Larner | ||
Activation of Protein Kinase A Inhibits IFN Induction of the Jak/Stat Pathway in U266 Cells | ![]() |
|
Journal of Biological Chemistry , Vol. 271, No. 9 (1996), 4585-88 |
E. Petricoin, M. David, K. Igarashi, C. Benjamin, L. Ling, S. Goelz, D.S. Finbloom and A.C. Larner | ||
Inhibition of Alpha Interferon but not Gamma Interferon Signal Transduction by Phorbol Esters is Mediated by a Tyrosine Phosphatase | ![]() |
|
Molecular and Cellular Biology, Vol.16, No.4 (1996), 1419-24 |
L. Stancato, M. David, C. Carter-Su, A. Larner and W. Pratt | ||
Preassociation of STAT1 with STAT2 and STAT3 in Seperate Signalling Complexes Prior to Cytokine Stimulation | ![]() |
|
Journal of Biological Chemistry, Vol.271, No. 8 (1996), 4134-37 |
M. David, H. Chen, S. Goelz, A. Larner and B. Neel | ||
Differential Regulation of the Interferon-a/b Stimulated JAK/STAT Pathway by the SH2-Domain Containing Tyrosine Phosphatase SHPTP1 | ![]() |
|
Molecular and Cellular Biology, Vol.15, No.12 (1995), 7050-58 |
M. David, E. Petricoin, C. Benjamin, R. Pine, M. Weber and A. Larner | ||
Requirement for MAP Kinase (ERK2) Activity in Interferon a/b-Stimulated Gene Expression Through STAT Proteins | ![]() |
|
Science Vol.269 (1995), p 1721 |
M. David | ||
Transcription Factors in Interferon Signaling | ![]() |
|
Pharmacology and Therapeutics Vol. 65, No. 2 (1995), 149-61 |
M. David, E.F. Petricoin, K. Igarashi, G.M. Feldman, D.S. Finbloom and A.C. Larner | ||
Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation | ![]() |
|
Proc. Natl. Acad. Sci. USA Vol. 91 (1994), 7174-78 |
D.S. Finbloom, E.F. Petricoin, R.H. Hackett, M. David, G.M. Feldman, K. Igarashi, M. Weber, M. Thorner, C.M. Silva and A.C. Larner | ||
Growth Hormone and Erythropoietin Differentially Activate DNA-Binding Proteins by Tyrosine Phosphorylation | ![]() |
|
Molecular and Cellular Biology, Vol. 14, No. 3 (1994), 2113-18 |
E.F. Petricoin, M. David, P. Grimley, A.C. Larner and S. VandePol | ||
Human Cancer Cell Lines Express A Negative Transcriptional Regulator of The Interferon Regulatory Factor Family of DNA-Binding Proteins | ![]() |
|
Molecular and Cellular Biology, Vol. 14, No. 2 (1994), 1477-86 |
G.M. Feldman, M.David, E.F. Petricoin III, A.C. Larner and D.S. Finbloom | ||
Cytokines which Associate with the Signal Transducer gp130 Activate the IFN Induced p91 Transcription Factor by Tyrosine Phosphorylation | ![]() |
|
Journal of Biological Chemistry, Vol. 269, No. 14 (1994), 10747-52 |
M. David, P. Grimley, D.S. Finbloom and A.C. Larner | ||
A Nuclear Tyrosine Phosphatase Downregulates Interferon Induced Gene Expression | ![]() |
|
Molecular and Cellular Biology, Vol.13, No.12 (1993), 7515-21 |
A.C. Larner, M. David, G.M. Feldman, K. Igarashi, R.H. Hackett, D.S. Webb, S.J. McLaughlin, E.F. Petricoin and D.S. Finbloom | ||
Tyrosine Phosphorylation of DNA-Binding Proteins by Multiple Cytokines | ![]() |
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Science Vol.261 (1993), p 1730-33 |
K. Igarashi, M. David, A.C. Larner and D.S. Finbloom | ||
In Vitro Activation of a Transcription Factor by IFNg Requires a Membrane associated Tyrosine Kinase and is Mimicked by Vanadate | ![]() |
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Molecular and Cellular Biology, Vol.13, No.7 (1993), 3984-89 |
K. Igarashi, M. David, D.S. Finbloom and A.C. Larner | ||
In Vitro Activation of The Transcription Factor GAF by IFN Gamma: Evidence For A Tyrosine Phosphatase/Kinase Signaling Cascade | ![]() |
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Molecular and Cellular Biology, Vol.13, No.3 (1993), 1634-40 |
M. David, G. Romero, J. Dixon and A.C. Larner | ||
In Vitro Activation of the Transcription Factor ISGF3 by IFNa Involves a Membrane Associated Tyrosine Phosphatase and Tyrosine Kinase | ![]() |
|
Journal of Biological Chemistry, Vol.268, No.9 (1993), 6593-99 |
M. David and A.C. Larner | ||
Activation of Transcription Factors by Interferon-alpha in a Cell-Free System | ![]() |
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Science Vol.257 (1992), p 813 |
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